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Human CellExp EGFR/ErbB1, human recombinant protein


Product info
Primary Accession P00533
Calculated MW This protein is fused with polyhistidine tag at the C-terminus, has a calculated MW of 69.5 kDa. The predicted N-terminus is Leu 25. DTT-reduced Protein migrates as 110-115 kDa due to glycosylation.
Additional Info
Gene ID 1956
Gene Symbol EGFR
Other Names EGFR, ERBB, ERBB1, HER1, PIG61, mENA
Gene Source Human
Source HEK293 cells
Assay&Purity SDS-PAGE; ≥95%
Assay2&Purity2 N/A;
Recombinant Yes
Results Measured by its binding ability in a functional ELISA. Immobilized human EGF at 10 µg/ml can bind human EGFR with a linear range of 0.5–750 ng/ml.
Target/Specificity ErbB1
Application Notes Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
Format Lyophilized
Storage -20°C; Lyophilized from 0.22 µm filtered solution in PBS, pH7.4. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization.
Citations (0)

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The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer.


Ullrich A.,et al.Nature 309:418-425(1984).
Ilekis J.V.,et al.Mol. Reprod. Dev. 41:149-156(1995).
Reiter J.L.,et al.Nucleic Acids Res. 24:4050-4056(1996).
Ilekis J.V.,et al.Gynecol. Oncol. 65:36-41(1997).
Reiter J.L.,et al.Genomics 71:1-20(2001).

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$ 225.00
Cat# PBV11019r
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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