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>   home   >   Products   >   Proteins   >   Human CellExp LRRC4 /NGL-2, human recombinant protein   

Human CellExp LRRC4 /NGL-2, human recombinant protein


Product info
Primary Accession Q9HBW1
Calculated MW This protein is fused with 6×His tag at the C-terminus, has a calculated MW of 55.6 kDa. The predicted N-terminus is Ala 39. DTT-reduced Protein migrates as 90-110 kDa due to glycosylation.
Additional Info
Gene ID 64101
Gene Symbol LRRC4
Other Names LRRC4, NGL-2, BAG, NAG14.
Gene Source Human
Source HEK293 cells
Assay&Purity SDS-PAGE; ≥92%
Assay2&Purity2 N/A;
Recombinant Yes
Results Measured by its binding ability in a functional ELISA. Immobilized Recombinant mouse Netrin-G2a Fc chimera at 4 µg/ml, can bind rhLRRC4 with an apparent KD < 10 nM.
Target/Specificity LRRC4 /NGL-2
Application Notes Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
Format Lyophilized
Storage -20°C; Lyophilized from 0.22 µm filtered solution in PBS, pH 7.4. Normally Mannitol or Trehalose is added as protectants before lyophilization.
Citations (0)

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LRRC4 (Leu-rich repeat/LRR-containing glycoprotein 4), LRRC4B and LRRC4C are post-synaptic adhesion molecules of the LRR protein family that induce excitatory synapse formation. LRRC4 is also known as Brain tumor-associated protein BAG, Netrin-G2 ligand (NGL-2), Nasopharyngeal carcinoma-associated gene 14 protein (NAG14), which contains 1 Ig-like (immunoglobulin-like) domain and 9 LRR (leucine-rich) repeats, 1 LRRCT domain, 1 LRRNT domain. LRRC4 / NGL-2 specifically expressed in brain. LRRC4 / NGL-2 regulates the formation of excitatory synapses through the recruitment of pre-and-postsynaptic proteins. LRRC4 / NGL-2 organize the lamina/pathway-specific differentiation of dendrites. LRRC4 / NGL-2 plays an important role for auditory synaptic responses and involved in the suppression of glioma.


Zhang Q.,et al.FEBS Lett. 579:3674-3682(2005).
Wang J.,et al.Thesis (2000), Zhongshan Medical University / Guangzhou, China.
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Scherer S.W.,et al.Science 300:767-772(2003).

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$ 195.00
$ 595.00
Cat# PBV11082r
(40 western blots)
Availability: 5-7days
Bulk Size
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