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>   home   >   Products   >   Proteins   >   Human CellExp FCER1A /FCE1A, human recombinant protein   

Human CellExp FCER1A /FCE1A, human recombinant protein

FCER1A, FCE1A, Ferris

Product info
Primary Accession P12319
Calculated MW This protein is fused with 6×His tag at the C-terminus, has a calculated MW of 21.9 kDa. The predicted N-terminus is Val 26. DTT-reduced Protein migrates as 40-60 kDa due to glycosylation.
Additional Info
Gene ID 2205
Gene Symbol FCER1A
Other Names FCER1A, FCE1A, Ferris
Gene Source Human
Source HEK293 cells
Assay&Purity SDS-PAGE; ≥90%
Assay2&Purity2 N/A;
Recombinant Yes
Results Measured by its binding ability in a functional ELISA. Immobilized human FCER1A at 2 µg/ml (100 µl/well). The concentration of Human IgE that produces 50% of the optimal binding response is found to be approximately 0.1 - 0.4 µg/ml.
Target/Specificity FCER1A /FCE1A
Application Notes Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
Format Lyophilized
Storage -20°C; Lyophilized from 0.22 µm filtered solution in PBS, pH 7.4. Normally Mannitol or Trehalose is added as protectants before lyophilization.
Citations (0)

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High affinity immunoglobulin epsilon receptor subunit alpha (FCER1A) is also known as Fc-epsilon RI-alpha (FcERI), IgE Fc receptor subunit alpha, FCE1A. FCER1A contains two Ig-like (immunoglobulin-like) domains. FCER1A binds to the Fc region of immunoglobulins epsilon and is a high affinity receptor. FCER1A is responsible for initiating the allergic response, which binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines. FCER1A plays a central role in allergic disease, coupling allergen and mast cell to initiate the inflammatory and immediate hypersensitivity responses that are characteristic of disorders such as hay fever and asthma.


Kochan J.,et al.Nucleic Acids Res. 16:3584-3584(1988).
Shimizu A.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:1907-1911(1988).
Yagi S.,et al.Eur. J. Biochem. 220:593-598(1994).
Padlan E.A.,et al.Receptor 2:129-144(1992).
Garman S.C.,et al.Cell 95:951-961(1998).

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$ 175.00
$ 575.00
Cat# PBV11094r
(40 western blots)
Availability: 5-7days
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