Human CellExp ICAM2 /CD102, human recombinant protein
ICAM2, CD102, Intercellular adhesion molecule 2
|Calculated MW||This protein is fused with 6×His tag at the C-terminus, has a calculated MW of 23.3 kDa. The predicted N-terminus is Ser 22. DTT-reduced Protein migrates as 40-63 kDa due to glycosylation.|
|Other Names||ICAM2, CD102, Intercellular adhesion molecule 2|
|Application Notes||Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.|
|Storage||-20°C; Lyophilized from 0.22 µm filtered solution in PBS, pH 7.4. Normally Mannitol or Trehalose is added as protectants before lyophilization.|
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Provided below are standard protocols that you may find useful for product applications.
Intercellular adhesion molecule 2 (ICAM2) is also known as CD antigen CD102, which belongs to the immunoglobulin superfamily and ICAM family. ICAM2 contains two Ig-like C2-type (immunoglobulin-like) domains. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 / CD102 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response; NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.
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