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Human CellExp Influenza A virus / Neuraminidase (NA) recombinant protein

NA, Neuraminidase

Product info
Primary Accession Q76UU8
Calculated MW Influenza A virus (A/Thailand/1(KAN-1)/2004 (H5N1)) Neuraminidase (NA) is fused with a polyhistidine tag at the N-terminus, and has a calculated MW of 46.1 kDa. The predicted N-terminus is His 36. DTT-reduced Protein migrates as 48 kDa in SDS-PAGE
Additional Info
Gene Symbol neuraminidase/NA
Other Names NA, Neuraminidase
Gene Source Influenza A Virus
Source HEK293 cells
Assay&Purity SDS-PAGE; ≥92%
Assay2&Purity2 N/A;
Recombinant Yes
Results Measured by its ability to cleave a fluorogenic substrate, 2'-(4-Methylumbelliferyl)-α-D-N-acetylneuraminic acid. One unit is defined as the amount of enzyme required to cleave 1 nmole of 2'-(4-Methylumbelliferyl)-α-D-N-acetylneuraminic acid per minute at pH 7.5 at 37°C
Target/Specificity Influenza A virus / Neuraminidase (NA)
Application Notes Centrifuge the vial prior to opening. Reconstitute in PBS, pH 7.4. Do not vortex.
Format Lyophilized
Storage -20°C; Lyophilized from 0.22 µm filtered solution in PBS, pH 7.4. Normally Mannitol or Trehalose are added as protectants before lyophilization.
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Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus. Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle. Neuraminidase, on the other hand, cleaves the HA-sialic acid bondage from the newly formed virions and the host cell receptors during budding. Neuraminidase thus is described as a receptor-destroying enzyme which facilitates virus release and efficient spread of the progeny virus from cell to cell.

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$ 225.00
Cat# PBV11127r
(40 western blots)
Availability: 5-7days
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