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Human CellExp DPPII / QPP / DPP7, human recombinant protein
DPPII, QPP, DPP7, DPP2, Dipeptidyl peptidase 2, Dipeptidyl aminopeptidase II
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9UHL4 |
|---|---|
| Calculated MW | This protein is fused with polyhistidine tag at the C-terminus, has a calculated MW of 53 kDa. The predicted N-terminus is Gly 22. DTT-reduced Protein migrates as 60-66 kDa due to glycosylation. |
| Gene ID | 29952 |
|---|---|
| Gene Symbol | DPP7 |
| Other Names | DPPII, QPP, DPP7, DPP2, Dipeptidyl peptidase 2, Dipeptidyl aminopeptidase II |
| Gene Source | Human |
| Source | HEK293 cells |
| Assay&Purity | SDS-PAGE; ≥95% |
| Assay2&Purity2 | N/A; |
| Recombinant | Yes |
| Results | >4000 pmol/min/ µg. |
| Target/Specificity | DPPII / QPP / DPP7 |
| Application Notes | Centrifuge the vial prior to opening. Reconstitute in PBS, pH 7.4. Do not vortex. |
| Format | Lyophilized |
| Storage | -20°C; Lyophilized from 0.22 µm filtered solution in 50 mM Tris, 150 mM NaCl, pH 7.5. Normally Mannitol or Trehalose are added as protectants before lyophilization. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Dipeptidyl peptidase 2 (DPP2 or DPP II) is also known as Dipeptidyl peptidase 7 (DPP7), Quiescent cell proline dipeptidase (QPP), which belongs to the peptidase S28 family. DPP7 / DPP2 is detected in seminal plasma (at protein level). When the pH is 5.5, Dipeptidyl peptidase 2 displays an optimum catalytic activity. DPP7 has low activity at pH 7 and is inactive at pH 8. DPP7 plays an important role in the degradation of some oligopeptides.
References
Underwood R.,et al.J. Biol. Chem. 274:34053-34058(1999).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Humphray S.J.,et al.Nature 429:369-374(2004).
Chiravuri M.,et al.J. Immunol. 165:5695-5702(2000).
Chen R.,et al.J. Proteome Res. 8:651-661(2009).
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