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>   home   >   Products   >   Proteins   >   Human CellExp Serpin E2 / PN1, human recombinant protein   

Human CellExp Serpin E2 / PN1, human recombinant protein

SERPINE2, Glia-derived nexin, GDN, Peptidase inhibitor 7, PI-7, Protease nexin 1, PN-1, Serpin E2, S

Product info
Primary Accession P07093
Calculated MW This protein is fused with a polyhistidine tag at the C-terminus, and has a calculated MW of 42.7 kDa. The predicted N-terminus is Ser 20. DTT-reduced Protein migrates as 45-48 kDa in SDS-PAGE due to glycosylation.
Additional Info
Gene ID 5270
Gene Symbol SERPINE2
Other Names SERPINE2, Glia-derived nexin, GDN, Peptidase inhibitor 7, PI-7, Protease nexin 1, PN-1, Serpin E2, SerpinE2, PI7
Gene Source Human
Source HEK293 cells
Assay&Purity SDS-PAGE; ≥92%
Assay2&Purity2 N/A;
Recombinant Yes
Target/Specificity Serpin E2 / PN1
Application Notes Centrifuge the vial prior to opening. Reconstitute in PBS, pH 7.4. Do not vortex.
Format Lyophilized
Storage -20°C; Lyophilized from 0.22 µm filtered solution in 20 mM NaAc, 100 mM NaCl, pH 6.5. Normally Mannitol or Trehalose are added as protectants before lyophilization.
Citations (0)

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SERPINE2 is also known as Glia-derived nexin (GDN), Peptidase inhibitor 7 (PI7), Protease nexin 1(PN1). SERPINE2 is a secreted glycoprotein which belongs to the serpin family. SerpinE1 is the primary physiological inhibitor of the two plasminogen activators urokinase (uPA) and tissue plasminogen activator (tPA). PAI-1 / GDN is also implicated in adipose tissue development. It suggests that PAI-1 inhibitors serve in the control of atherothrombosis. Defects in Serpin E1 / PN1 are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency) which is characterized by abnormal bleeding due to SerpinE1 defect in the plasma.


Sommer J.,et al.Biochemistry 26:6407-6410(1987).
Gloor S.M.,et al.Cell 47:687-693(1986).
McGrogan M.,et al.Biotechnology (N.Y.) 6:172-177(1988).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).

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$ 255.00
Cat# PBV11134r
(40 western blots)
Availability: 5-7days
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