|Calculated MW||86 kDa|
|Other Names||Hp 1-1|
|Storage||-20°C; Lyophilized as a salt-free solid.|
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Provided below are standard protocols that you may find useful for product applications.
Of the three haptoglobin phenotypes, Hp 1-1 is the most effective in binding free hemoglobin and in suppressing the inflammatory responses associated with free hemoglobin. Hp 1-1 protects against vascular complications in diabetes, is associated with sickle cell anemia, and is more common than other phenotypes in cases of cirrhosis. Individuals who are phenotype 1-1 have the highest concentration of haptoglobin in plasma.
van der Straten A.,et al.EMBO J. 2:1003-1007(1983).
Yang F.,et al.Proc. Natl. Acad. Sci. U.S.A. 80:5875-5879(1983).
van der Straten A.,et al.FEBS Lett. 168:103-107(1984).
Brune J.L.,et al.Nucleic Acids Res. 12:4531-4538(1984).
Bensi G.,et al.EMBO J. 4:119-126(1985).
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