Transferrin (HOLO), Human Plasma recombinant protein
Transferrin, Siderophilin, TF, DKFZp781D0156, PRO1557, PRO2086
|Calculated MW||80.0 kDa|
|Other Names||Transferrin, Siderophilin, TF, DKFZp781D0156, PRO1557, PRO2086|
|Storage||-20°C; Lyophilized from 20 mM Na phosphate, pH 7.4 and 150 mM NaCI.|
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Provided below are standard protocols that you may find useful for product applications.
Transferrin is a monomeric glycoprotein found in plasma at an average concentration of 250 mg/100ml. The specific iron-binding protein in plasma, it has a role in the transportation and distribution of iron among the body organs, in iron metabolism and in prevention of iron loss via the kidney. Stored in bone marrow as TF-bound iron, it also possesses bacteriostatic and fungistatic activity. Clinically, decreases in transferrin are observed in congenital disorders, newborns, inflammatory diseases, hypo-proteinemias and nephritic syndrome; increases are found in pregnancy, iron-deficiency anemias and inoculation hepatitis. Transferrin is required by all types of cells in cultures for maximal growth. It is, therefore, an important factor used in defined culture media.
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Hosino A.,et al.Comp. Biochem. Physiol. 113B:491-497(1996).
Xu C.S.,et al.Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
Aldred A.R.,et al.Biochem. Biophys. Res. Commun. 122:960-965(1984).
Huggenvik J.I.,et al.Endocrinology 120:332-340(1987).
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