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Transferrin (HOLO), Human Plasma recombinant protein

Transferrin, Siderophilin, TF, DKFZp781D0156, PRO1557, PRO2086

     
  • SPECIFICATION
  • CITATIONS
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Product info
Primary Accession P12346
Calculated MW 80.0 kDa
Additional Info
Gene ID 24825
Gene Symbol TF
Other Names Transferrin, Siderophilin, TF, DKFZp781D0156, PRO1557, PRO2086
Gene Source Human
Source Human Plasma
Assay&Purity SDS-PAGE; ≥95%
Assay2&Purity2 N/A;
Recombinant No
Target/Specificity Transferrin (HOLO)
Format Lyophilized
Storage -20°C; Lyophilized from 20 mM Na phosphate, pH 7.4 and 150 mM NaCI.
Citations (0)
citation

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Background

Transferrin is a monomeric glycoprotein found in plasma at an average concentration of 250 mg/100ml. The specific iron-binding protein in plasma, it has a role in the transportation and distribution of iron among the body organs, in iron metabolism and in prevention of iron loss via the kidney. Stored in bone marrow as TF-bound iron, it also possesses bacteriostatic and fungistatic activity. Clinically, decreases in transferrin are observed in congenital disorders, newborns, inflammatory diseases, hypo-proteinemias and nephritic syndrome; increases are found in pregnancy, iron-deficiency anemias and inoculation hepatitis. Transferrin is required by all types of cells in cultures for maximal growth. It is, therefore, an important factor used in defined culture media.

References

Escriva H.,et al.Biochem. J. 307:47-55(1995).
Hosino A.,et al.Comp. Biochem. Physiol. 113B:491-497(1996).
Xu C.S.,et al.Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
Aldred A.R.,et al.Biochem. Biophys. Res. Commun. 122:960-965(1984).
Huggenvik J.I.,et al.Endocrinology 120:332-340(1987).

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Discontinued
Cat# PBV11151r-100
Size:

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