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Hemopexin, Rat Serum recombinant protein

Beta-1B-glycoprotein, HPX

     
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Product info
Primary Accession P20059
Calculated MW 57.0 kDa
Additional Info
Gene ID 58917
Gene Symbol HPX
Other Names Beta-1B-glycoprotein, HPX
Gene Source Rat
Source Rat Serum
Assay&Purity SDS-PAGE; ≥95%
Assay2&Purity2 N/A;
Recombinant No
Target/Specificity Hemopexin
Format Lyophilized
Storage -20°C; Lyophilized from 11.9 mM phosphate, 137 mM NaCl, 2.7 mM KCl, pH 7.4.
Citations (0)
citation

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Background

Hemopexin is a single-chain protein belonging to the family of blood transport proteins. It binds to heme released into the bloodstream during the degradation process. Recent studies have demonstrated that hemopexin acts as an extracellular antioxidant against hemoglobin-mediated damage in inflammation. Hemopexin protects against heme toxicity and conserves and recycles iron. Abnormal levels of hemopexin are associated with hemolytic anemia, chronic neuromuscular disease, and acute intermittent porphyria.

References

Nikkilae H.,et al.Biochemistry 30:823-829(1991).
Nagae Y.,et al.Biochem. Biophys. Res. Commun. 185:420-429(1992).
Wellner D.,et al.Biochem. Biophys. Res. Commun. 155:622-625(1988).
Swerts J.P.,et al.J. Biol. Chem. 267:10596-10600(1992).
Lubec G.,et al.Submitted (NOV-2006) to UniProtKB.

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Discontinued
Cat# PBV11154r-100
Size:

Ordering Information

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