|Calculated MW||57.0 kDa|
|Other Names||Beta-1B-glycoprotein, HPX|
|Storage||-20°C; Lyophilized from 11.9 mM phosphate, 137 mM NaCl, 2.7 mM KCl, pH 7.4.|
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Provided below are standard protocols that you may find useful for product applications.
Hemopexin is a single-chain protein belonging to the family of blood transport proteins. It binds to heme released into the bloodstream during the degradation process. Recent studies have demonstrated that hemopexin acts as an extracellular antioxidant against hemoglobin-mediated damage in inflammation. Hemopexin protects against heme toxicity and conserves and recycles iron. Abnormal levels of hemopexin are associated with hemolytic anemia, chronic neuromuscular disease, and acute intermittent porphyria.
Nikkilae H.,et al.Biochemistry 30:823-829(1991).
Nagae Y.,et al.Biochem. Biophys. Res. Commun. 185:420-429(1992).
Wellner D.,et al.Biochem. Biophys. Res. Commun. 155:622-625(1988).
Swerts J.P.,et al.J. Biol. Chem. 267:10596-10600(1992).
Lubec G.,et al.Submitted (NOV-2006) to UniProtKB.
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