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FTO, human recombinant protein

Fat Mass and Obesity-associated Protein; FATSO.

Product info
Primary Accession Q9C0B1
Concentration 0.2
Calculated MW ~65 kDa (SDS-PAGE). Human FTO (aa 2-505) is fused at the N-terminus to a His-tag.
Additional Info
Gene ID 79068
Gene Symbol FTO
Other Names Fat Mass and Obesity-associated Protein; FATSO.
Gene Source Human
Source E. coli
Assay&Purity SDS-PAGE; ≥90%
Assay2&Purity2 N/A;
Recombinant Yes
Target/Specificity FTO
Format Liquid
Storage -20°C; 0.2 mg/ml of 0.2 µm-filtered solution in 55 mM Tris-Cl, pH 8.2 containing 150 mM NaCl.
Citations (0)

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FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse ‘fused toes’ mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol.


Nagase T.,et al.DNA Res. 7:347-355(2000).
Martin J.,et al.Nature 432:988-994(2004).
Dina C.,et al.Nat. Genet. 39:724-726(2007).
Frayling T.M.,et al.Science 316:889-894(2007).
Jia G.,et al.FEBS Lett. 582:3313-3319(2008).

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$ 215.00
Cat# PBV11166r
(40 western blots)
Availability: 5-7days
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