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NMNAT1, human recombinant protein

Nicotinamide Mononucleotide Adenylyl-transferase 1, NMN Adenylyltransferase 1; NaMN Adenylyltransfer

Product info
Primary Accession Q9HAN9
Concentration 1
Calculated MW ~33.3 kDa (monomer). Human full-length NMNAT1 (aa 1-279) is fused at the N-terminus to a His-tag.
Additional Info
Gene ID 64802
Gene Symbol NMNAT1
Other Names Nicotinamide Mononucleotide Adenylyl-transferase 1, NMN Adenylyltransferase 1; NaMN Adenylyltransferase 1; EC
Gene Source Human
Source E. coli
Assay&Purity SDS-PAGE; ≥95%
Assay2&Purity2 N/A;
Recombinant Yes
Results ≥ 5U/mg protein. One unit is defined as the amount of enzyme that synthesizes 1 µmol of NAD+ per min.
Target/Specificity NMNAT1
Format Liquid
Storage -20°C; 1 mg/ml in 50 mM sodium phosphate, pH 8.0 containing 300 mM sodium chloride, 2 mM DTT and 10% glycerol.
Citations (0)

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This is the nuclear NMNAT isoform. It catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. It can also use the deamidated form of nicotinic acid mononucleotide (NAMN) as substrate with the same efficiency. It interacts with PARP-1/ARTD1. It protects against axonal degeneration following mechanical or toxic insults. It is widely expressed.


Schweiger M.,et al.FEBS Lett. 492:95-100(2001).
Emanuelli M.,et al.J. Biol. Chem. 276:406-412(2001).
Fernando F.S.,et al.Gene 284:23-29(2002).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).

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$ 240.00
$ 795.00
Cat# PBV11170r-10
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