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Wnt-2, human recombinant protein
INT1L1, IRP, Int-1-like protein 1, Int-1-related protein
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P09544 |
|---|---|
| Calculated MW | 39.9 kDa |
| Gene ID | 7472 |
|---|---|
| Gene Symbol | WNT2 |
| Other Names | INT1L1, IRP, Int-1-like protein 1, Int-1-related protein |
| Gene Source | Human |
| Source | E. coli |
| Assay&Purity | SDS-PAGE; ≥90% |
| Assay2&Purity2 | N/A; |
| Recombinant | Yes |
| Target/Specificity | WNT2 |
| Application Notes | Reconstitute in sterile ddH2O to a concentration ≥ 100 µg/ml. |
| Format | Lyophilized |
| Storage | -20°C; Lyophilized without additives |
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Provided below are standard protocols that you may find useful for product applications.
Background
This protein belongs to the Wnt family of proteins. The WNT gene family consists of structurally related genes that encode secreted signaling proteins involved in the Wnt signaling pathway. Wnt gene family members, including Wnt-1 through Wnt-10, play a key role in regulating cellular growth and differentiation. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Wnt-2 is expressed in brain in the thalamus, in fetal and adult lung and in the placenta.
References
Wainwright B.J.,et al.EMBO J. 7:1743-1748(1988).
Farrall M.,et al.Submitted (APR-1988) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Kalnine N.,et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
Hillier L.W.,et al.Nature 424:157-164(2003).
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