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GAPDH, human recombinant protein

GAPDH, Glyceraldehyde 3-phosphate dehydrogenase

Product info
Primary Accession P04406.3
Calculated MW 36.0 kDa
Additional Info
Gene ID 2597
Gene Symbol GD3
Other Names Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (EC (Peptidyl-cysteine S-nitrosylase GAPDH) (EC 2.6.99.-)
Gene Source Human
Source E. coli
Assay&Purity SDS-PAGE; ≥95%
Assay2&Purity2 HPLC;
Recombinant Yes
Format Liquid
Storage -20°C; 1 mg/ml solution containing 20 mM Tris pH-8, 1 mM EDTA, 1 mM DTT, and 20% glycerol.
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Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) is a catalytic enzyme normally known to play a role in glycolysis. GAPDH exists as a tetramer composed of 36-kDa subunits and has a range of intracellular functions. GAPDH catalyzes the reversible reduction of 1,3-bisphosphoglycerate to glyceraldehyde 3-phosphophate in the presence of NADPH. Besides functioning as a glycolytic enzyme in cytoplasm, GAPDH has function in intracellular processes such as membrane fusion, microtubule bundling, phosphotransferase activity, nuclear RNA export, DNA replication and DNA repair. GAPDH catalyzes a vital energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The enzyme exists as a tetramer of identical chains. Recombinant human GAPDH produced in E.Coli is a single, non-glycosylated polypeptide chain containing 335 amino acids and having a molecular mass of 36 kDa. The GAPDH is purified by proprietary chromatographic techniques.

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$ 4,450.00
$ 225.00
Cat# PBV11206r
(40 western blots)
Availability: 5-7days
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