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Active recombinant protein Human CETP
BPIFF, Cholesteryl ester transfer protein, HDLCQ10, Lipid transfer protein I
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P11597 |
|---|---|
| Calculated MW | 55 kDa |
| Gene ID | 1071 |
|---|---|
| Gene Symbol | CETP |
| Other Names | BPIFF, Cholesteryl ester transfer protein, HDLCQ10, Lipid transfer protein I |
| Gene Source | Human |
| Source | Insect cell |
| Assay&Purity | SDS-PAGE; ≥90% |
| Assay2&Purity2 | HPLC; |
| Recombinant | Yes |
| Application Notes | Reconstitute in sterile water at 2 mg/ml. |
| Format | Lyophilized powder |
| Storage | -20°C; Lyophilized from a Buffer containing 10 mM Tris and 150 mM NaCl. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Cholesteryl ester transfer protein (CETP), also called plasma lipid transfer protein, is a plasma protein that facilitates the transport of cholesteryl esters and triglycerides between the lipoproteins. It collects triglycerides from very-low-density (VLDL) or low-density lipoproteins (LDL) and exchanges them for cholesteryl esters from high-density lipoproteins (HDL), and vice versa. Inhibition of CETP has been proposed as a strategy to raise HDL cholesterol levels, a potential an approach to retarding atherogenesis and a strategy to reduce cardiovascular risk.
References
Drayna D.,et al.Nature 327:632-634(1987).
Agellon L.B.,et al.Biochemistry 29:1372-1376(1990).
Rieder M.J.,et al.Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases.
Oliveira C.F.O.,et al.J. Biol. Chem. 271:31831-31838(1996).
Williams S.,et al.Gene 197:101-107(1997).
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