Register or Login
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Proteins   >   Active recombinant protein Human beta-Secretase 1 - BACE-1   

Active recombinant protein Human beta-Secretase 1 - BACE-1


Product info
Primary Accession P56817
Calculated MW 47 kDa
Additional Info
Gene ID 23621
Gene Symbol BACE1
Other Names Beta-secretase 1, Aspartyl protease 2, ASP2, Beta-site amyloid precursor protein cleaving enzyme 1, Beta-site APP cleaving enzyme 1, Memapsin-2, Membrane-associated aspartic protease 2, Aspartic-like protease 56 kDa, Aspartyl protease 1, Beta-site amyloid precursor protein cleaving enzyme 2, Down region aspartic protease, Memapsin-1, Membrane-associated aspartic protease 1, Theta-secretase
Gene Source Human
Source Insect cell
Assay&Purity SDS-PAGE; ≥90%
Assay2&Purity2 HPLC;
Recombinant Yes
Application Notes Use 20 µl sterile D.I. water to dissolve 10 µg of protein for a final conc of 0.5 µg/ µl. For further dilution, use 10 mM Tris, pH 8.0.
Format Lyophilized powder
Storage -70°C; Supplied as a lyophilized powder.
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abgent antibody to, and receive a free "I Love Antibodies" mug.


β-Secretase, also called BACE1 (β-site of APP cleaving enzyme) or memapsin-2 is an aspartic-acid protease important in the pathogenesis of Alzheimer's disease, and in the formation of myelin sheaths in peripheral nerve cells. The transmembrane protein, contains two active site aspartate residues in its extracellular protein domain and may function as a dimer..


Vassar R.,et al.Science 286:735-741(1999).
Sinha S.,et al.Nature 402:537-540(1999).
Yan R.,et al.Nature 402:533-537(1999).
Hussain I.,et al.Mol. Cell. Neurosci. 14:419-427(1999).
Michel B.,et al.Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases.

Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at

$ 195.00
$ 595.00
$ 8,950.00
Cat# PBV11212r-5
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
Request Quote Here

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaCentral AmericaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSouth KoreaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamWorldwideOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609
USA Headquarters
(888) 735-7227 / (858) 622-0099 or (858) 875-1900

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
“Crown Flash”  50 % off on 1,800+ Crown Antibodies. PromoCode:<span class=text-red> FLASH50
Terms & Conditions