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>   home   >   Products   >   Proteins   >   Active recombinant protein Human beta-Secretase 1 - BACE-1   

Active recombinant protein Human beta-Secretase 1 - BACE-1


Product info
Primary Accession P56817
Calculated MW 47 kDa
Additional Info
Gene ID 23621
Gene Symbol BACE1
Other Names Beta-secretase 1, Aspartyl protease 2, ASP2, Beta-site amyloid precursor protein cleaving enzyme 1, Beta-site APP cleaving enzyme 1, Memapsin-2, Membrane-associated aspartic protease 2, Aspartic-like protease 56 kDa, Aspartyl protease 1, Beta-site amyloid precursor protein cleaving enzyme 2, Down region aspartic protease, Memapsin-1, Membrane-associated aspartic protease 1, Theta-secretase
Gene Source Human
Source Insect cell
Assay&Purity SDS-PAGE; ≥90%
Assay2&Purity2 HPLC;
Recombinant Yes
Application Notes Use 20 µl sterile D.I. water to dissolve 10 µg of protein for a final conc of 0.5 µg/ µl. For further dilution, use 10 mM Tris, pH 8.0.
Format Lyophilized powder
Storage -70°C; Supplied as a lyophilized powder.
Citations (0)

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β-Secretase, also called BACE1 (β-site of APP cleaving enzyme) or memapsin-2 is an aspartic-acid protease important in the pathogenesis of Alzheimer's disease, and in the formation of myelin sheaths in peripheral nerve cells. The transmembrane protein, contains two active site aspartate residues in its extracellular protein domain and may function as a dimer..


Vassar R.,et al.Science 286:735-741(1999).
Sinha S.,et al.Nature 402:537-540(1999).
Yan R.,et al.Nature 402:533-537(1999).
Hussain I.,et al.Mol. Cell. Neurosci. 14:419-427(1999).
Michel B.,et al.Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases.

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$ 195.00
$ 595.00
$ 8,950.00
Cat# PBV11212r
(40 western blots)
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