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HDAC-3, human recombinant protein

HDAC-3, HDAC3, HDAC 3, Histone deacetylase 3

Product info
Primary Accession O15379
Concentration 0.5U/ µl
Calculated MW 51.1kDa
Additional Info
Gene ID 8841
Gene Symbol HDAC3
Other Names Histone deacetylase 3, HD3, RPD3-2, SMAP45
Gene Source Human
Source Sf9 insect cells
Assay&Purity SDS-PAGE; ≥50%
Assay2&Purity2 HPLC;
Recombinant Yes
Format Liquid
Storage -80°C; rh-HDAC-3 is supplied with N-term His-tag as a liquid in 25 mM Tris, pH 7.5, 100 mM NaCl, 2.7 mM KCl, 3 mM MgCl2, 10 % glycerol.
Citations (0)

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Human Histone Deacetylase 3 (HDAC3) is a member of the class I Histone Deacetylases. HDACs are important enzymes for the transcriptional regulation of gene expression in eukaryotic cells. HDACs catalyze the removal of acetyl groups from lysines near the N-termini of histones. Human HDACs have been implicated in a variety of human diseases such as cardiomyopathy, osteodystrophy, neurodegenerative disorders, aging and cancer. Like other class I and II HDAC members, the activity of HDAC3 is sensitive to HDAC inhibitor Trichostatin A (TSA).


Dangond F.,et al.Biochem. Biophys. Res. Commun. 242:648-652(1998).
Yang W.-M.,et al.J. Biol. Chem. 272:28001-28007(1997).
Emiliani S.,et al.Proc. Natl. Acad. Sci. U.S.A. 95:2795-2800(1998).
Mahlknecht U.,et al.Genomics 56:197-202(1999).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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$ 295.00
$ 895.00
Cat# PBV11214r
(40 western blots)
Availability: 5-7days
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