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Bromodomain Testis-specific Protein (BrdT), human recombinant protein

Recombinant Human Bromodomain Testis-specific Protein (BrdT)

     
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  • CITATIONS
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Product info
Primary Accession Q58F21
Calculated MW 13.9 kDa (117aa, 22-138 +NT-His Tag)
Additional Info
Gene ID 676
Gene Symbol BRDT
Other Names BrdT, Cancer/testis antigen 9, CT9, RING3-like protein
Gene Source Human
Source E. coli
Assay&Purity SDS-PAGE; ≥98%
Assay2&Purity2 N/A;
Recombinant Yes
Target/Specificity BRDT
Format Liquid
Storage -80°C; rh-BrdT is supplied as a solution in 50 mM Tris, pH 8.0, 150 mM NaCl and 10% Glycerol.
Citations (0)

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Background

BrdT is similar to the RING3 protein family. It possesses 2 bromodomain motifs and a PEST sequence. The bromodomain is found in proteins that regulate transcription. BrdT drives a meiotic and post-meiotic gene expression program. It also controls the genome-wide post-meiotic genome reorganization that occurs after histone hyperacetylation in elongating spermatids. It may play a role in the transcriptional regulation of spermatogenesis. It also seems to have a structural ATP-independent role in the reorganization of acetylated chromatin. BioVision’s recombinant protein includes Bromo 1 domain (22-138 aa) with N-terminal His-tag.

References

Jones M.H.,et al.Genomics 45:529-534(1997).
Zheng Y.,et al.Int. J. Mol. Med. 15:315-321(2005).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

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$ 145.00
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$ 2,950.00
Cat# PBV11217r
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