Bromodomain-containing Protein 4 (BrD4, domain 49-170aa), human recombinant protein
Recombinant Human Bromodomain-containing Protein 4 (BrD4, domain 49-170aa)
|Calculated MW||14.6 kDa (122 aa, 49-170 aa)|
|Other Names||BRD4, Protein HUNK1, HUNK1|
|Storage||-80°C; rh-BrD4 is supplied as a solution in 50mM Tris, pH 8.0, 150 mM NaCl and 10% glycerol.|
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Provided below are standard protocols that you may find useful for product applications.
BrD4 protein is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. It plays a role in a process governing chromosomal dynamics during mitosis. BioVision’s BrD4 recombinant protein includes Bromo 2 domain (49-170 aa) with an N-terminal His-tag.
French C.A.,et al.Am. J. Pathol. 159:1987-1992(2001).
Weber B.,et al.Submitted (MAR-1997) to the EMBL/GenBank/DDBJ databases.
Grimwood J.,et al.Nature 428:529-535(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
French C.A.,et al.Cancer Res. 63:304-307(2003).
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