Bromodomain-containing Protein 4 (BrD4, domain 342-460 aa), human recombinant protein
Recombinant Human Bromodomain-containing Protein 4 (BrD4)
|Calculated MW||12.4 kDa (119 aa, 342-460 aa + NT- His Tag)|
|Other Names||BRD4, Protein HUNK1, HUNK1|
|Storage||-80°C; rh-BrD4 is supplied as a solution in 50 mM Tris, pH 8.0, 150 mM NaCl and 10% Glycerol.|
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BrD4 protein is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. It plays a role in a process governing chromosomal dynamics during mitosis. BioVision's BrD4 recombinant protein includes Bromo 2 domain (342-460 aa) with a N-terminal His-tag.
French C.A.,et al.Am. J. Pathol. 159:1987-1992(2001).
Weber B.,et al.Submitted (MAR-1997) to the EMBL/GenBank/DDBJ databases.
Grimwood J.,et al.Nature 428:529-535(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
French C.A.,et al.Cancer Res. 63:304-307(2003).
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