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>   home   >   Products   >   Proteins   >   BRD9 bromodomain (21-137 aa) (GST-tagged), human recombinant protein   

BRD9 bromodomain (21-137 aa) (GST-tagged), human recombinant protein

Human recombinant BRD9 bromodomain (21-137 aa) (GST-tagged)

Product info
Primary Accession Q9H8M2
Calculated MW 40.7 kDa (21-137 aa + GST Tag)
Additional Info
Gene ID 65980
Gene Symbol BRD9
Other Names Bromodomain containing 9
Gene Source Human
Source E. coli
Assay&Purity SDS-PAGE; ≥95%
Assay2&Purity2 N/A;
Recombinant Yes
Target/Specificity BRD9
Format Liquid
Storage -80°C; 50 mM Tris, pH 7.5, containing 500 mM sodium chloride, 5% glycerol, and 5 mM β-mercaptoethanol.
Citations (0)

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The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. A bromodomain is a protein domain that recognizes acetylated lysine residues such as those on the N-terminal tails of histones. This recognition is often a prerequisite for protein-histone association and chromatin remodeling. These domains function in the linking of protein complexes to acetylated nucleosomes, thereby controlling chromatin structure and gene expression. Thus, bromodomains serve as “readers” of histone acetylation marks regulating the transcription of target promoters. The BET family of proteins, defined by tandem Bromodomains and an Extra Terminal domain, include BRD2, BRD3, BRD4, and BRDT. The BET proteins play a key role in many cellular processes, including inflammatory gene expression, mitosis, and viral/host interactions. Human BRD9 contains a single bromodomain and has five isoforms that are produced by alternative splicing. This product contains the bromodomain region of BRD9.This protein can be used for the study of bromodomain binding assays, screening inhibitors, and selectivity profiling.


Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Schmutz J.,et al.Nature 431:268-274(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Behrends U.,et al.Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.

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$ 175.00
$ 595.00
Cat# PBV11225r
(40 western blots)
Availability: 5-7days
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