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SIRT7 (2-400 aa) (His-tagged), Human recombinant protein

SIRT7 (2-400 aa) (His-tagged), Human recombinant

Product info
Primary Accession Q9NRC8
Calculated MW 49.3 kDa (2-400 aa, NT His Tag)
Additional Info
Gene ID 51547
Gene Symbol SIRT7
Other Names NAD-dependent deacetylase 7; SIR2-like protein 7; Sirtuin 7; SIR2L7; Silent Information Regulator 7
Gene Source Human
Source E. coli
Assay&Purity SDS-PAGE; ≥85%
Assay2&Purity2 HPLC;
Recombinant Yes
Target/Specificity SIRT7
Format Liquid
Storage -80°C; 50 mM sodium phosphate, pH 7.2, 100 mM sodium chloride, 5 mM DTT, and 20% glycerol.
Citations (0)

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The sirtuins represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs) and have been shown to catalyze a reaction that couples lysine deacetylation to the formation of nicotinamide and O-acetyl-ADP-ribose from NAD+ and the abstracted acetyl group. There are seven human sirtuins, which have been designated SIRT1-SIRT7. Recently, SIRT7 has been shown to activate transcription by RNA polymerase I and deacetylate p53. SIRT7 prevents progressive functional deterioration of the heart, and is suggested to play an important role in regulation of stress responses and cell death in the heart.


Frye R.A.,et al.Biochem. Biophys. Res. Commun. 273:793-798(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:1045-1049(2006).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
de Nigris F.,et al.Br. J. Cancer 86:917-923(2002).

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$ 145.00
$ 295.00
Cat# PBV11251r
(40 western blots)
Availability: 5-7days
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