Exodus-2, Mouse recombinant protein
C-C motif chemokine 21, 6Ckine, Beta-chemokine exodus-2, Secondary lymphoid-tissue chemokine, SLC, S
|Calculated MW||12 kDa|
|Other Names||C-C motif chemokine 21, 6Ckine, Beta-chemokine exodus-2, Secondary lymphoid-tissue chemokine, SLC, Small-inducible cytokine A21|
|Results||200 ng/mL- 600 ng/mL.|
|Sequence||SDGGGQDCCL KYSQKKIPYS IVRGYRKQEP SLGCPIPAIL FSPRKHSKPE LCANPEEGWV QNLMRRLDQP PAPGKQSPGC RKNRGTSKSG KKGKGSKGCK RTEQTQPSRG|
|Application Notes||Recommended reconstitution in sterile water at a concentration of 0.1 mg/mL|
|Storage||-20°C; Lyophilized powder. Recommended reconstitution in sterile water at a concentration of 0.1 mg/mL|
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Provided below are standard protocols that you may find useful for product applications.
Exodus-2, also known as CCL21 and 6Ckine, is a novel chemokine produced at high levels in human lymph node tissue and the spleen. 6Ckine signals through the CCR7 receptor to recruit thymocytes and activated T cells in vitro, but is not known to be chemotactic for monocytes. Human and mouse Exodus-2 share > 85% amino acid homology. Recombinant mouse Exodus-2 is a nonglycosylated protein, containing 110 amino acids, with a molecular weight of 12 kDa.
Hedrick J.A.,et al.J. Immunol. 159:1589-1593(1997).
Tanabe S.,et al.J. Immunol. 159:5671-5679(1997).
Vassileva G.,et al.J. Exp. Med. 190:1183-1188(1999).
Nakano H.,et al.J. Immunol. 166:361-369(2001).
Carninci P.,et al.Science 309:1559-1563(2005).
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