Exodus-2, Mouse recombinant protein
C-C motif chemokine 21, 6Ckine, Beta-chemokine exodus-2, Secondary lymphoid-tissue chemokine, SLC, S
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P84444 |
---|---|
Calculated MW | 12 kDa |
Gene ID | 18829 |
---|---|
Gene Symbol | CCL21 |
Other Names | C-C motif chemokine 21, 6Ckine, Beta-chemokine exodus-2, Secondary lymphoid-tissue chemokine, SLC, Small-inducible cytokine A21 |
Gene Source | Mouse |
Source | E. coli |
Assay&Purity | SDS-PAGE; ≥98% |
Assay2&Purity2 | HPLC; |
Recombinant | Yes |
Results | 200 ng/mL- 600 ng/mL. |
Sequence | SDGGGQDCCL KYSQKKIPYS IVRGYRKQEP SLGCPIPAIL FSPRKHSKPE LCANPEEGWV QNLMRRLDQP PAPGKQSPGC RKNRGTSKSG KKGKGSKGCK RTEQTQPSRG |
Target/Specificity | CCL21 |
Application Notes | Recommended reconstitution in sterile water at a concentration of 0.1 mg/mL |
Format | Lyophilized powder |
Storage | -20°C; Lyophilized powder. Recommended reconstitution in sterile water at a concentration of 0.1 mg/mL |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Exodus-2, also known as CCL21 and 6Ckine, is a novel chemokine produced at high levels in human lymph node tissue and the spleen. 6Ckine signals through the CCR7 receptor to recruit thymocytes and activated T cells in vitro, but is not known to be chemotactic for monocytes. Human and mouse Exodus-2 share > 85% amino acid homology. Recombinant mouse Exodus-2 is a nonglycosylated protein, containing 110 amino acids, with a molecular weight of 12 kDa.
References
Hedrick J.A.,et al.J. Immunol. 159:1589-1593(1997).
Tanabe S.,et al.J. Immunol. 159:5671-5679(1997).
Vassileva G.,et al.J. Exp. Med. 190:1183-1188(1999).
Nakano H.,et al.J. Immunol. 166:361-369(2001).
Carninci P.,et al.Science 309:1559-1563(2005).
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.