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Prekallikrein, Human Plasma recombinant protein

Fletcher factor, Kininogenin.

Product info
Primary Accession P03952
Calculated MW 86 kDa
Additional Info
Gene ID 3818
Gene Symbol KLK
Other Names Fletcher factor, Kininogenin.
Gene Source Human
Source Human Plasma
Assay&Purity SDS-PAGE; ≥95%
Assay2&Purity2 N/A;
Recombinant No
Results Lot dependent
Target/Specificity Prekallikrein
Format Liquid
Storage -80°C; In 4 mM Sodium Acetate-HCl, 0.15 M NaCl, pH 5.3.
Citations (0)

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Prekallikrein is the glycosylated single chain zymogen precursor of the plasma serine protease kallikrein. Plasma prekallikrein circulates with kininogen and is activated by Factor XIIa in the intrinsic coagulation pathway. Kallikrein activates plasminogen in fibrinolysis and cleaves kininogen in the bradykinin system of vasodilation. Prekallikrein deficiency is rare and causes increased activated partial thromboplastin time. Elevated plasma prekallikrein is associated with diabetes and cardiovascular disease.


Chung D.W.,et al.Biochemistry 25:2410-2417(1986).
Yu H.,et al.Genomics 69:225-234(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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$ 145.00
Cat# PBV11261r
(40 western blots)
Availability: 5-7days
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