|Calculated MW||58.8 kDa|
|Other Names||Stuart factor, Stuart-Prower factor|
|Storage||-80°C; In 20 mM Tris-HCl, 0.1 M NaCl, 1 mM Benzamidine pH 7.4.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Factor X is a vitamin K-dependent protein zymogen which is synthesized in the liver and circulates in plasma as a two chain molecule linked by a disulfide bond. Prior to secretion into plasma, post-translational modifications produce 11 gamma-carboxyglutamic acid (gla) residues and a single b-hydroxyaspartic acid residue, which are located within the NH2-terminal light chain. The light chain also contains two epidermal growth factor (EGF) homology domains. The COOH-terminal heavy chain of factor X contains most of the carbohydrate moieties, as well as the latent serine protease domain. The activation of factor X is catalyzed by either the intrinsic factor Xase complex (factor IXa, factor VIIIa, cellular surface and calcium ions) or the extrinsic factor Xase complex (factor VIIa, tissue factor, cellular surface and calcium ions).
Messier T.L.,et al.Gene 99:291-294(1991).
Leytus S.P.,et al.Biochemistry 25:5098-5102(1986).
Fung M.R.,et al.Proc. Natl. Acad. Sci. U.S.A. 82:3591-3595(1985).
Kaul R.K.,et al.Gene 41:311-314(1986).
McMullen B.A.,et al.Biochemistry 22:2875-2884(1983).
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.