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Factor Xa, Human Plasma recombinant protein

Stuart factor, Stuart-Prower factor

     
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Product info
Primary Accession P00742
Calculated MW 46.00 kDa
Additional Info
Gene ID 2159
Gene Symbol F10
Other Names Stuart factor, Stuart-Prower factor
Gene Source Human
Source Human Plasma
Assay&Purity SDS-PAGE; ≥95%
Assay2&Purity2 N/A;
Recombinant No
Results Lot dependent
Target/Specificity Factor Xa
Format Liquid
Storage -80°C; In 20 mM Bis Tris, 0.7 M NaCl pH 6.0.
Citations (0)
citation

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Background

Factor Xa is a serine endoproteinase and a member of the S1 peptidase family. Factor Xa plays a critical role in the coagulation cascade by catalyzing the proteolytic conversion of prothrombin to active thrombin. Factor Xa’s prothrombin conversion activity is greatly enhanced in vivo when complexed with Factor V, calcium ions and phospholipids on the activated platelet surface.

References

Messier T.L.,et al.Gene 99:291-294(1991).
Leytus S.P.,et al.Biochemistry 25:5098-5102(1986).
Fung M.R.,et al.Proc. Natl. Acad. Sci. U.S.A. 82:3591-3595(1985).
Kaul R.K.,et al.Gene 41:311-314(1986).
McMullen B.A.,et al.Biochemistry 22:2875-2884(1983).

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Discontinued
Cat# PBV11265r-400
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