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Factor XII, Human Plasma

Stuart factor, Stuart-Prower factor

Product info
Primary Accession P00748
Calculated MW 80.00 kDa
Additional Info
Gene ID 2161
Gene Symbol F12
Other Names Stuart factor, Stuart-Prower factor
Gene Source Human
Source Human Plasma
Assay&Purity SDS-PAGE; ≥95%
Assay2&Purity2 N/A;
Recombinant No
Results Lot dependent
Target/Specificity Factor XII
Format Liquid
Storage -80°C; In 4 mM Sodium Acetate-HCl, 0.15 M NaCl, pH 5.3.
Citations (0)

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Human Factor XII is a single chain glycoprotein with a molecular weight of about 80,000. Once activated, principally from the action of kallikrein, Factor XII is converted into an active serine protease (Factor α-Xlla) that functions in the in vivo initiation of blood coagulation, fibrinolysis, and kinin formation. Human Factor XII has been purified by ion exchange chromatography.


Cool D.E.,et al.J. Biol. Chem. 262:13662-13673(1987).
Schmutz J.,et al.Nature 431:268-274(2004).
Tripodi M.,et al.Nucleic Acids Res. 14:3146-3146(1986).
Cool D.E.,et al.J. Biol. Chem. 260:13666-13676(1985).
Que B.G.,et al.Biochemistry 25:1525-1528(1986).

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$ 245.00
Cat# PBV11266r-250
Availability: 5-7days
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