|Calculated MW||80.00 kDa|
|Other Names||Stuart factor, Stuart-Prower factor|
|Storage||-80°C; In 4 mM Sodium Acetate-HCl, 0.15 M NaCl, pH 5.3.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Human Factor XII is a single chain glycoprotein with a molecular weight of about 80,000. Once activated, principally from the action of kallikrein, Factor XII is converted into an active serine protease (Factor α-Xlla) that functions in the in vivo initiation of blood coagulation, fibrinolysis, and kinin formation. Human Factor XII has been purified by ion exchange chromatography.
Cool D.E.,et al.J. Biol. Chem. 262:13662-13673(1987).
Schmutz J.,et al.Nature 431:268-274(2004).
Tripodi M.,et al.Nucleic Acids Res. 14:3146-3146(1986).
Cool D.E.,et al.J. Biol. Chem. 260:13666-13676(1985).
Que B.G.,et al.Biochemistry 25:1525-1528(1986).
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