|Calculated MW||80.00 kDa|
|Other Names||Hageman factor|
|Storage||-80°C; In 4 mM Sodium Acetate-HCl, 0.15 M NaCl, pH 5.3.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Human Factor α-XIIa is a serine protease responsible for the activation of Factor XI to XIa in the contact activation system. Human Factor XII and prekallikrein are thought to be involved in a reciprocal activation mechanism in which Factor XIIa activates prekallikrein to kallikrein, which in turn converts Factor XII to XIIa. Factor XIIa activates Factor XI to XIa thereby triggering the Contact Factor cascade.
Cool D.E.,et al.J. Biol. Chem. 262:13662-13673(1987).
Schmutz J.,et al.Nature 431:268-274(2004).
Tripodi M.,et al.Nucleic Acids Res. 14:3146-3146(1986).
Cool D.E.,et al.J. Biol. Chem. 260:13666-13676(1985).
Que B.G.,et al.Biochemistry 25:1525-1528(1986).
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