Register or Login
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Proteins   >   Active Transglutaminase 2 (His-tagged), human recombinant protein   

Active Transglutaminase 2 (His-tagged), human recombinant protein

TG2, tTG, tissue transglutaminase, transglutaminase C, TGC, protein-glutamine-gamma-glutamyltransfer

Product info
Primary Accession P21980
Calculated MW 79.5 kDa (1-687 aa + N-terminal polyhistidine tag).
Additional Info
Gene ID 7052
Gene Symbol TGM2
Other Names TG2, tTG, tissue transglutaminase, transglutaminase C, TGC, protein-glutamine-gamma-glutamyltransferase, TGM2
Gene Source Human
Source E.coli
Assay&Purity SDS-PAGE; ≥90%
Assay2&Purity2 HPLC;
Recombinant Yes
Results >400 mU/mg
Sequence 1-687 aa of human transglutaminase 2 + N-terminal polyhistidine tag
Target/Specificity Transglutaminase 2
Application Notes Reconstitute to 0.1-0.5 mU/ µl in 20 mM Tris, 120 mM NaCl, 10 mM DTT, pH 7.5 containing 20% glycerol. Aliquot and store at –80°C. Avoid repeated freezing and thawing cycles.
Format Lyophilized powder
Storage -80°C; Lyophilized from 5 mg/ml solution in a proprietary buffer.
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abgent antibody to, and receive a free "I Love Antibodies" mug.


Tissue transglutaminase, a 78-kDa calcium dependent enzyme (EC, is found both in the intracellular and the extracellular spaces of various types of tissues. TG2 crosslinks proteins between the ε-amino group of a lysine residue and the γ-carboxamide group of glutamine residue, creating an inter- or intramolecular bond that is highly resistant to proteolysis (protein degradation). TG2 also possesses deamidation, GTP-binding/hydrolyzing, and isopeptidase activities. Intracellular TG2 is thought to play an important role in apoptosis, while extracellular TG2 has been linked to cell adhesion, ECM stabilization, wound healing, receptor signaling, cellular proliferation, and cellular motility.


Gentile V.,et al.J. Biol. Chem. 266:478-483(1991).
Fraij B.M.,et al.J. Biol. Chem. 267:22616-22623(1992).
Fraij B.M.,et al.Biochim. Biophys. Acta 1306:63-74(1996).
Bayardo M.P.,et al.Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).

Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at

$ 169.00
$ 499.00
Cat# PBV11276r-10
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
Request Quote Here

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaCentral AmericaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSouth KoreaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamWorldwideOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609
USA Headquarters
(888) 735-7227 / (858) 622-0099 or (858) 875-1900

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
“Crown Flash”  50 % off on 1,800+ Crown Antibodies. PromoCode:<span class=text-red> FLASH50
Terms & Conditions