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P38delta, Active recombinant protein

p38, mitogen-activated protein kinase 13

Product info
Primary Accession O15264
Concentration 0.1
Calculated MW 71.0 kDa
Additional Info
Gene ID 5603
Gene Symbol MAPK13
Other Names p38, mitogen-activated protein kinase 13
Source Baculovirus (Sf9 insect cells)
Assay&Purity SDS-PAGE; ≥80%
Assay2&Purity2 HPLC;
Recombinant Yes
Format Liquid
Storage -80°C; Recombinant proteins in storage buffer (50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol).
Citations (0)

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Mitogen-activated protein kinase (MAPK) cascades represent one of the major signal systems used by eukaryotic cells to transduce extracellular signals into cellular responses, and involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The stress-activated protein kinase 4 (SAPK4), or p38 delta, is a member of the MAPK family that are activated by chemical and environmental stresses as well as by proinflammatory cytokines. SAPK4 has a TGY dual phosphorylation motif and is activated in response to cellular stresses and proinflammatory cytokines (1). MAP kinase kinases 3, and 6 can phosphorylate and activate this kinase. Transcription factor ATF2, and microtubule dynamics regulator stathmin have been shown to be the substrates of this kinase (2).

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$ 295.00
Cat# PBV11329r
(40 western blots)
Availability: 5-7days
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