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p38 beta, Active recombinant protein
p38, mitogen-activated protein kinase 11
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q15759 |
|---|---|
| Concentration | 0.1 |
| Calculated MW | 71.0 kDa |
| Gene ID | 5600 |
|---|---|
| Gene Symbol | MAPK11 |
| Other Names | p38, mitogen-activated protein kinase 11 |
| Source | Baculovirus (Sf9 insect cells) |
| Assay&Purity | SDS-PAGE; ≥90% |
| Assay2&Purity2 | HPLC; |
| Recombinant | Yes |
| Format | Liquid |
| Storage | -80°C; Recombinant protein stored in 50mM Tris-HCl, pH 7.5, and 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol. |
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Provided below are standard protocols that you may find useful for product applications.
Background
p38-β is a member of the p38 MAP kinase family and is activated by both proinflammatory cytokines and environmental stress (1). The p38-β is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase (2). Alternatively spliced transcript variants encoding the same protein have been observed.
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