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PKC gamma, Active recombinant protein

PKC, protein kinase C, gammaprotein kinase C

     
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Product info
Primary Accession P05129
Concentration 0.1
Calculated MW 105.0 kDa
Additional Info
Gene ID 5582
Gene Symbol PRKCG
Other Names PKC, protein kinase C, gammaprotein kinase C
Source Baculovirus (Sf9 insect cells)
Assay&Purity SDS-PAGE; ≥80%
Assay2&Purity2 HPLC;
Recombinant Yes
Format Liquid
Storage -80°C; Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Citations (0)
citation

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Background

PKCγ is a member of the protein kinase C (PKC) family of serine- and threonine-specific protein kinases that can phosphorylate a wide variety of protein targets known to be involved in diverse cellular signaling pathways. In the brain, PKC is translocated to cell membranes during ischemia and is rapidly removed or degraded during the second otherwise lethal ischemic insult in preconditioned brains. This suggest that ischemic preconditioning enhances downregulation of cell signaling mediated by PKC and may thereby provide neuroprotection (1).

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Discontinued
Cat# PBV11337r-5
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