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FRK, Active recombinant protein

FRK, fyn-related kinase

Product info
Primary Accession P42685
Concentration 0.1
Calculated MW 60.0 kDa
Additional Info
Gene ID 2444
Gene Symbol FRK
Other Names FRK, fyn-related kinase, FYN-related kinase, Nuclear tyrosine protein kinase RAK, Protein-tyrosine kinase 5
Source Baculovirus (Sf9 insect cells)
Assay&Purity SDS-PAGE; ≥90%
Assay2&Purity2 HPLC;
Recombinant Yes
Format Liquid
Storage -80°C; Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Citations (0)

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FRK (fyn-related kinase) or Rak is a nuclear tyrosine kinase and member of the Src sub-family. Restricted expression of FRK is detected in a broad range of cell lines with highest levels in epithelial cells. Increased expression of FRK has been shown in breast and renal cell carcinoma cell lines. In addition the retinoblastoma tumor susceptibility gene product pRb associates with FRK in vitro and in vivo (1). Overexpression of FRK in β-cells from the pancreas increases the susceptibility of these cells to β-cell-toxic events (hallmark of Type I diabetes)(2).

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$ 295.00
Cat# PBV11338r
(40 western blots)
Availability: 5-7days
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