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PI3K (p85⍺) Protein recombinant protein

PI3K (p85⍺) Protein, PI3K, PI3 kinase

Product info
Primary Accession P27986
Concentration 0.2
Calculated MW 86.0 kDa
Additional Info
Gene ID 5295
Gene Symbol PIK3R1
Other Names PI3K (p85⍺) Protein, PI3K, PI3 kinase
Source Baculovirus (Sf9 insect cells)
Assay&Purity SDS-PAGE; ≥95%
Assay2&Purity2 HPLC;
Recombinant Yes
Format Liquid
Storage -80°C; Recombinant protein in storage buffer (50 mM sodium phosphate, pH 7.0, 300 mM NaCl, 2 mM DTT, 150 mM imidazole, 0.1 mM PMSF, 25 % glycerol.).
Citations (0)

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The PI3K comprises of a 110 kDa catalytic subunit and a 85 kDa regulatory subunit. A number of isoforms of the 110 kDa catalytic subunit and the 85 kDa regulatory subunit exist in cells. p85αmodulates the interaction between PI3K and platelet-derived growth factor receptor (1). Furthermore, estrogen receptor isoform ER-alpha binds in a ligand-dependent manner to the p85α regulatory subunit of PI3K. Stimulation with estrogen increases ER-alpha-associated PI3K activity, leading to the activation of protein kinase B/AKT and endothelial nitric oxide synthase (eNOS) (2).

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$ 3,950.00
$ 295.00
Cat# PBV11339r
(40 western blots)
Availability: 5-7days
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