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RSK2, Active recombinant protein

RSK, ribosomal protein S6 kinase, 90kDa, polypeptide 3

Product info
Primary Accession P51812
Concentration 0.1
Calculated MW 112.0 kDa
Additional Info
Gene ID 6197
Gene Symbol RPS6KA3
Other Names RSK, ribosomal protein S6 kinase, 90kDa, polypeptide 3, MAP kinase-activated protein kinase 1c
Source Baculovirus (Sf9 insect cells)
Assay&Purity SDS-PAGE; ≥90%
Assay2&Purity2 HPLC;
Recombinant Yes
Format Liquid
Storage -80°C; Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
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RSK2 is a member of the RSK (ribosomal S6 kinase) family that are growth factor-regulated serine/threonine kinases. RSK2 has been shown to mediate growth factor signaling via RAS and MAPK leading to the induction of CREB serine-133 phosphorylation and activation of gene expression (1). Mutations in RSK2 have been shown to be responsible for Coffin-Lowry syndrome (CLS) which is a X-linked disorder characterized by severe psychomotor retardation, facial and digital dysmorphisms, and progressive skeletal deformations (2).

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$ 295.00
Cat# PBV11340r
(40 western blots)
Availability: 5-7days
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