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MET, Active recombinant protein

MET

     
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Product info
Primary Accession X96786
Concentration 0.1
Calculated MW 74.0 kDa
Additional Info
Gene Symbol MET
Other Names MET, HGF/SF receptor, Proto-oncogene c-Met, Scatter factor receptor, Short name=SF receptor, Tyrosine-protein kinase Met
Source Baculovirus (Sf9 insect cells)
Assay&Purity SDS-PAGE; ≥90%
Assay2&Purity2 HPLC;
Recombinant Yes
Format Liquid
Storage -80°C; Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Citations (0)
citation

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Background

MET is a proto-oncogene that encodes a transmembrane growth factor receptor which is a heterodimer of two disulphide linked chains of 50 kd (α) and 145 kd (β). MET is widely expressed in the kidney, brain, lung, skin, and embryonic tissue (1). Hepatocyte growth factor (HGF) binds to MET and activates its tyrosine kinase activity. MET is overexpressed and activated in a variety of human cancers including pancreatic, colon, gastric, cervical and ovarian cancers and has been shown to be involved in tumor cell migration and invasion (2).

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Discontinued
Cat# PBV11342r-5
Size:

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