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MRCK beta, Active recombinant protein

MRCK, CDC42 binding protein kinase beta (DMPK-like)

     
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Product info
Primary Accession Q9Y5S2
Concentration 0.1
Calculated MW 73.0 kDa
Additional Info
Gene ID 9578
Gene Symbol CDC42
Other Names MRCK, CDC42 binding protein kinase beta (DMPK-like), DMPK-like beta, Myotonic dystrophy kinase-related CDC42-binding kinase beta
Source Baculovirus (Sf9 insect cells)
Assay&Purity SDS-PAGE; ≥90%
Assay2&Purity2 HPLC;
Recombinant Yes
Format Liquid
Storage -80°C; Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Citations (0)
citation

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Background

Myotonic Dystrophy Kinase-Related cdc42-binding kinase β (MRCKb) belongs to the DMPK subfamily (1). The myotonic dystrophy kinase-related kinases and myotonic dystrophy kinase-related Cdc42 binding kinase (MRCK) are effectors of RhoA and Cdc42, respectively, where they are involved in actin cytoskeletal reorganization and neurite outgrowth (2). Effects of the repeat expansion on the DMPK gene may be responsible for muscle and heart features of Myotonic Dystrophy.

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Discontinued
Cat# PBV11343r-5
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