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Glucokinase, human pancreatic, recombinant protein

Product info
Primary Accession P35557
Concentration 39.3
Calculated MW 53.1 kDa
Additional Info
Gene ID 2645
Gene Symbol GCK
Other Names Glucokinase, Hexokinase type IV, HK IV, Hexokinase-4, HK4, Hexokinase-D
Gene Source Human pancreas
Source E.coli
Assay&Purity SDS-PAGE; ≥80%
Assay2&Purity2 HPLC;
Recombinant Yes
Format Liquid
Storage -80°C; 50 mM potassium phosphate pH 7.4, 50 mM sodium chloride, 0.5 mM DTT, 0.5 mM EDTA, and 2.5% glycerol.
Citations (0)

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Glucose is phosphorylated to glucose-6-phosphate by glucokinases. This gene is alternatively spliced to generate three different forms of the enzyme; one found in the pancreas and two found in the liver. The main function of this gene is to regulate carbohydrate metabolism. Recombinant human pancreatic Glucokinase (Accession# NP_000153)) has a C-terminal FLAG tag and has 470 amino acid residues. It can be useful for studies including enzyme kinetics, activator screening and kinase selectivity.


Tanizawa Y.,et al.Mol. Endocrinol. 6:1070-1081(1992).
Tanizawa Y.,et al.Proc. Natl. Acad. Sci. U.S.A. 88:7294-7297(1991).
Nishi S.,et al.Diabetologia 35:743-747(1992).
Koranyi L.I.,et al.Diabetes 41:807-811(1992).
Stoffel M.,et al.Proc. Natl. Acad. Sci. U.S.A. 89:7698-7702(1992).

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$ 145.00
Cat# PBV11347r
(40 western blots)
Availability: 5-7days
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