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GPT2/ALT2, human recombinant protein

Alanine aminotransferase 2, AAT2, ALT2

     
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Product info
Primary Accession Q8TD30
Concentration 0.5
Calculated MW 60.3 kDa (546 aa, 1-523 aa + His Tag)
Additional Info
Gene ID 84706
Gene Symbol GPT2
Other Names Alanine aminotransferase 2, AAT2, ALT2
Gene Source Human
Source E.coli
Assay&Purity SDS-PAGE; ≥90%
Assay2&Purity2 N/A;
Recombinant Yes
Results Specific activity is > 30 unit/mg
Sequence MGSSHHHHHH SSGLVPRGSH MGSMQRAAAL VRRGCGPRTP SSWGRSQSSA AAEASAVLKV RPERSRRERI LTLESMNPQV KAVEYAVRGP IVLKAGEIEL ELQRGIKKPF TEVIRANIGD AQAMGQQPIT FLRQVMALCT YPNLLDSPSF PEDAKKRARR ILQACGGNSL GSYSASQGVN CIREDVAAYI TRRDGGVPAD PDNIYLTTGA SDGISTILKI LVSGGGKSRT GVMIPIPQYP LYSAVISELD AIQVNYYLDE ENCWALNVNE LRRAVQEAKD HCDPKVLCII NPGNPTGQVQ SRKCIEDVIH FAWEEKLFLL ADEVYQDNVY SPDCRFHSFK KVLYEMGPEY SSNVELASFH STSKGYMGEC GYRGGYMEVI NLHPEIKGQL VKLLSVRLCP PVSGQAAMDI VVNPPVAGEE SFEQFSREKE SVLGNLAKKA KLTEDLFNQV PGIHCNPLQG AMYAFPRIFI PAKAVEAAQA HQMAPDMFYC MKLLEETGIC VVPGSGFGQR EGTYHFRMTI LPPVEKLKTV LQKVKDFHIN FLEKYA
Target/Specificity GPT2/ALT2
Format Liquid
Storage -20°C; 0.5 mg/ml solution 20 mM Tris-HCl buffer (pH 7.5), 30% glycerol, 0.2 M NaCl and 2 mM DTT.
Citations (0)

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Background

Alanine aminotransferase 2, also known as GPT2, catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. Subsequently, they play a key role in the intermediary metabolism of glucose and amino acids. GPT2 expression is high in muscle, fat and kidney. Recombinant human GPT2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

References

Yang R.-Z.,et al.Genomics 79:445-450(2002).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Martin J.,et al.Nature 432:988-994(2004).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).

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$ 375.00
Cat# PBV11365r-50
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