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NME2, human recombinant protein

Nucleoside diphosphate kinase B, NDPK-B, NDPKB, NM23-H2, NM23B.

     
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Product info
Primary Accession P22392
Concentration 1
Calculated MW 17.2 kDa (152 aa, 1-152 aa)
Additional Info
Gene ID 4831
Gene Symbol NME2
Other Names Nucleoside diphosphate kinase B, NDPK-B, NDPKB, NM23-H2, NM23B.
Gene Source Human
Source E.coli
Assay&Purity SDS-PAGE; ≥95%
Assay2&Purity2 N/A;
Recombinant Yes
Results Specific activity is > 340 units/ml
Sequence MANLERTFIA IKPDGVQRGL VGEIIKRFEQ KGFRLVAMKF LRASEEHLKQ HYIDLKDRPF FPGLVKYMNS GPVVAMVWEG LNVVKTGRVM LGETNPADSK PGTIRGDFCI QVGRNIIHGS DSVKSAEKEI SLWFKPEELV DYKSCAHDWV YE
Target/Specificity NME2
Format Liquid
Storage -20°C; 1 mg/ml solution in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol and 1 mM DTT
Citations (0)

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Background

NME2, also known as NM23B, is a heterodimeric protein functioning as a nucleoside diphosphate (NDP) kinase. NME1 and NME2 comprise the 152 amino acid A and B polypeptide chains of the NM23 enzyme, respectively. NME2 is identical to the beta subunit of human erythrocyte NDP kinase. NDP kinases are involved in the synthesis of nucleoside triphosphates, and NM23 may act in the regulation of signal transduction by complexing with G proteins, causing activation/inactivation of developmental pathways. Recombinant human NME2 protein was expressed in E.coli and purified by using conventional chromatography techniques.

References

Stahl J.A.,et al.Cancer Res. 51:445-449(1991).
Gilles A.-M.,et al.J. Biol. Chem. 266:8784-8789(1991).
Postel E.H.,et al.Science 261:478-480(1993).
Valentijn L.J.,et al.Genomics 87:483-489(2006).
Zody M.C.,et al.Nature 440:1045-1049(2006).

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$ 285.00
Cat# PBV11383r
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