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Human CellExpCNTFR/CNTFR-alpha, human recombinant protein


Product info
Primary Accession P26992
Calculated MW This protein rh CNTFR alpha is fused with polyhistidine tag at the C-terminus, has a calculated MW of 36.9 kDa. The predicted N-terminus is Gln 23. DTT-reduced Protein migrates as 45-48 kDa due to glycosylation.
Additional Info
Gene ID 1271
Gene Symbol CNTFR
Other Names CNTFR, CNTF R alpha
Gene Source Human
Source HEK 293 cells
Assay&Purity SDS-PAGE; ≥95%
Assay2&Purity2 N/A;
Recombinant Yes
Results Measured by its binding ability in a functional ELISA. Immobilized human CTNFR at 10 µg/ml (100 µl/well) can bind biotinylated human CNTF with a linear ranger of 3.2 - 100 ng/ml.
Target/Specificity CNTFR/CNTFR-alpha
Application Notes Centrifuge the vial prior to opening. Reconstitute in PBS, pH 7.4. Do not vortex.
Format Lyophilized
Storage -20°C; Lyophilized from 0.22 µm filtered solution in PBS, pH 7.4. Normally Mannitol or Trehalose are added as protectants before lyophilization.
Citations (0)

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Ciliary neurotrophic factor receptor subunit alpha (CNTFR or CNTFR-alpha) belongs to the type I cytokine receptor family and type 3 subfamily. CNTFR contains two fibronectin type-III domains and one Ig-like C2-type (immunoglobulin-like) domain. This receptor and its cognate ligand support the survival of neurons. This receptor is most closely related to the interleukin-6 receptor. This receptor possesses an unusual attachment to the cell membrane through a glycophosphatidylinositol linkage.


Davis S.,et al.Science 253:59-63(1991).
Valenzuela D.M.,et al.Genomics 25:157-163(1995).
Kalnine N.,et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
Humphray S.J.,et al.Nature 429:369-374(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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$ 175.00
$ 575.00
Cat# PBV11395r
(40 western blots)
Availability: 5-7days
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