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>   home   >   Products   >   Proteins   >   Aprotinin, Active, Bovine recombinant protein (AOF)   

Aprotinin, Active, Bovine recombinant protein (AOF)

BPTI, Basic protease inhibitor, Pancreatic trypsin inhibitor

Product info
Primary Accession P00974
Calculated MW 9.7 kDa (36-93 aa + N-terminal Poly-his tag)
Additional Info
Gene Symbol BPI
Other Names BPTI, Basic protease inhibitor, Pancreatic trypsin inhibitor
Gene Source Bovine
Source E. coli
Assay&Purity SDS-PAGE ; ≥90%
Assay2&Purity2 N/A;
Recombinant Yes
Target/Specificity Aprotinin
Application Notes Centrifuge the vial prior to opening at low speed. Reconstitute in water to a concentration of 1 mg/ml. The solution can then be diluted into PBS or other aqueous buffers and store at 4°C for 1 week or –20°C for future use. For long-term storage, it is recommended to add a carrier protein (e.g., 0.1% BSA). Avoid repeated freezing and thawing cycles.
Format Lyophilized
Storage -20°C; Lyophilized from 5 mg/ml solution in PBS
Citations (0)

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Aprotinin inhibits the activity of several proteolytic enzymes such as chymotrypsin, kallikrein, plasmin and trypsin. It is present in blood and in most tissues, with a high concentration in lung, inhibits pro-inflammatory cytokine release and maintains glycoprotein homeostasis. In platelets, Aprotinin reduces glycoprotein loss (e.g., GpIb, GpIIb/IIIa), while in granulocytes it prevents the expression of pro-inflammatory adhesive glycoproteins. Aprotinin is a natural proteinase inhibitor polypeptide consisting of fifty-eight amino acids arranged in a single polypeptide chain, cross-linked by three disulfide bridges. BioVision’s Recombinant Bovine Aprotinin is an animal-origin free protein purified by proprietary chromatographic techniques.


Creighton T.E.,et al.J. Mol. Biol. 194:11-22(1987).
Creighton T.E.,et al.Cold Spring Harb. Symp. Quant. Biol. 52:511-519(1987).
Kingston I.B.,et al.Biochem. J. 233:443-450(1986).
Anderson S.,et al.Proc. Natl. Acad. Sci. U.S.A. 80:6838-6842(1983).
Kassell B.,et al.Biochem. Biophys. Res. Commun. 20:463-468(1965).

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$ 60.00
$ 100.00
Cat# PBV11413r-1
Availability: 5-7days
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