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Human CellExp KLF4-TAT, Human Recombinant

Krueppel-like factor 4, Epithelial zinc finger protein EZF, Gut-enriched krueppel-like factor, EZF,

     
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Product info
Primary Accession O43474
Calculated MW 51.7 kDa
Additional Info
Gene ID 9314
Other Names Krueppel-like factor 4, Epithelial zinc finger protein EZF, Gut-enriched krueppel-like factor, EZF, GKLF
Gene Source Human
Source HEK293 cells
Assay&Purity SDS-PAGE;>90%
Assay2&Purity2 HPLC;≥90%
Recombinant Yes
Sequence Isoform 2 of Krueppel-like factor 4 with 13-residue C-terminal TAT peptide (GGYGRKKRRQRRR)
Target/Specificity KLF4-TAT
Application Notes Reconstitute in sterile deionized water to a concentration of 0.1-1.0 mg/ml. Do not vortex. Additional carrier protein (example 0.1% BSA) is recommended for long term storage.
Format Dry powder
Storage -80°C;Lyophilized powder
Citations (0)
citation

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Background

Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription.

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Discontinued
Cat# PBV11465r-20
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