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Human CellExp™ CD163, Human recombinant

CD163, M130

     
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Product info
Primary Accession Q86VB7
Calculated MW This protein is fused with a 6× His tag at C-terminus and has a calculated MW of 110.4 kDa. The protein migrates as 135-140 kDa in SDS-PAGE due to glycosylation.
Additional Info
Gene ID 9332
Other Names CD163, M130
Gene Source Human
Source HEK 293 cells
Assay&Purity SDS-PAGE;≥95%
Assay2&Purity2 N/A;≥95%
Recombinant Yes
Target/Specificity CD163
Application Notes Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml
Format Lyophilized
Storage -20°C;Lyophilized from 0.22 µm filtered solution in PBS, pH 7.4. Normally Mannitol or Trehalose is added as protectants before lyophilization.
Citations (0)

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Background

Scavenger receptor cysteine-rich type 1 protein M130 (CD163) is also known as hemoglobin scavenger receptor, which is a scavenger receptor for the hemoglobin-haptoglobin complex. CD163 has also been shown to mark cells of monocyte/macrophage lineage. A soluble form of the receptor exists in plasma, commonly denoted sCD163. sCD163 is generated by ectodomain shedding of the membrane bound receptor. sCD163 is upregulated in a large range of inflammatory diseases including liver cirrhosis, type 2 diabetes, macrophage activation syndrome, Gaucher’s disease, sepsis, HIV infection, rheumatoid arthritis and Hodgkin Lymphoma.

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$ 220.00
$ 630.00
Cat# PBV11470r-10
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