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CSTA, human recombinant
Cystatin-A, STF1, STFA
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | NP_005204 |
|---|---|
| Concentration | 1 mg/ml |
| Calculated MW | This protein is fused with a 6× His tag at N-terminus and has a calculated MW of 13.1 kDa. |
| Other Names | Cystatin-A, STF1, STFA |
|---|---|
| Gene Source | Human |
| Source | E.coli |
| Assay&Purity | SDS-PAGE;>95% |
| Assay2&Purity2 | N/A;>95% |
| Recombinant | Yes |
| Sequence | MGSSHHHHHH SSGLVPRGSH MIPGGLSEAK PATPEIQEIV DKVKPQLEEK TNETYGKLEA VQYKTQVVAG TNYYIKVRAG DNKYMHLKVF KSLPGQNEDL VLTGYQVDKN KDDELTGF |
| Target/Specificity | CSTA |
| Application Notes | In 20 mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 10% glycerol |
| Format | Liquid |
| Storage | -20°C;Liquid |
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Provided below are standard protocols that you may find useful for product applications.
Background
CSTA, also known as Stefin A, is thiol protease inhibitors that form complexes with papain and the cathepsins B, H and L. The protein is one of the precursor proteins of the cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. CSTA is thought to be a tumor suppressor, since an inverse correlation seems to exist between the level of CSTA and tumor progression, in several malignancies
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