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Human CellExp™ CD28, Human recombinant

CD28, Tp44

     
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Product info
Primary Accession AAH93698
Calculated MW This protein is fused with a Fc tag at C-terminus and has a calculated MW of 41.8 kDa.
Additional Info
Other Names CD28, Tp44
Gene Source Human
Source HEK 293 cells
Assay&Purity SDS-PAGE;≥92%
Assay2&Purity2 N/A;≥92%
Recombinant Yes
Target/Specificity CD28
Application Notes Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml
Format Lyophilized
Storage -20°C;Lyophilized
Citations (0)

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Background

T-cell-specific surface glycoprotein CD28 is also known as TP44, is a single-pass type I membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. is one of the molecules expressed on T cells that provide co-stimulatory signals, which are required for T cell activation. CD28 is the receptor for CD80 (B7.1) and CD86 (B7.2). When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells.

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$ 150.00
$ 590.00
Cat# PBV11481r-10
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