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>   home   >   Products   >   Proteins   >   Human CellExp™ B7-H3 / CD276, Human recombinant   

Human CellExp™ B7-H3 / CD276, Human recombinant

B7-H3, CD276, B7 homolog 3

     
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Product info
Primary Accession Q5ZPR3-2
Calculated MW This protein is fused with a Fc tag at C-terminus and has a calculated MW of 50 kDa.
Additional Info
Other Names B7-H3, CD276, B7 homolog 3
Gene Source Human
Source HEK 293 cells
Assay&Purity SDS-PAGE;>95%
Assay2&Purity2 N/A;>95%
Recombinant Yes
Target/Specificity CD276
Application Notes Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml
Format Lyophilized
Storage -20°C;Lyophilized
Citations (0)

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Background

B7 homolog 3 (B7-H3), a member of the immunoglobulin superfamily, is also known CD276, which contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domains. B7-H3 may participate in the regulation of T-cell-mediated immune response. B7-H3 also plays a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. Furthermore, B7-H3 is involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. It could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy.

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$ 170.00
$ 375.00
Cat# PBV11483r-10
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