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>   home   >   Products   >   Proteins   >   Human CellExp™ OX40 Ligand / TNFSF4, Human recombinant   

Human CellExp™ OX40 Ligand / TNFSF4, Human recombinant

OX40L,TNFSF4,CD252

     
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
Product info
Primary Accession NP_003317
Calculated MW This protein is fused with a Fc tag at C-terminus and has a calculated MW of 20 kDa.
Additional Info
Other Names OX40L, TNFSF4, CD252
Gene Source Human
Source HEK 293 cells
Assay&Purity SDS-PAGE;>95%
Assay2&Purity2 N/A;>95%
Recombinant Yes
Target/Specificity TNFRSF4
Application Notes Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml
Format Lyophilized
Storage -20°C;Lyophilized
Citations (0)

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Background

Tumor necrosis factor ligand superfamily member 4 (TNFSF4) is also known as glycoprotein Gp34, OX40 ligand (OX40L), TAX transcriptionally-activated glycoprotein 1 and CD252, which belongs to the tumor necrosis factor family. TNFSF4 is the ligand for CD134 and is expressed on such cells as DC2s (a subtype of dendritic cells) enabling amplification of Th2 cell differentiation. The interaction of TNFSF4-TNFSF4 is involved in the pathogenesis of multiple autoimmune and inflammatory diseases such as systemic lupus erythematosus (SLE), carotid artery disease and cancer. Furthermore, similar to other TNF superfamily members, membrane-bound OX40 Ligand (TNFSF4) exists as a homotrimer. Human TNFSF4 shares 46% amino acid sequence identity with its mouse counterpart.

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$ 130.00
$ 375.00
Cat# PBV11487r-10
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