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MAGEA3, human recombinant

CT1.3, HIP8, HYPD, MAGE3, MZ2 D

     
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Product info
Primary Accession NP_005353.1
Concentration 1 mg/ml
Calculated MW This protein is fused with a 6× His tag at N-terminus and has a calculated MW of 37.1 kDa.
Additional Info
Other Names CT1.3, HIP8, HYPD, MAGE3, MZ2 D
Gene Source Human
Source E.coli
Assay&Purity SDS-PAGE;≥90%
Assay2&Purity2 N/A;≥90%
Recombinant Yes
Sequence MGSSHHHHHH SSGLVPRGSH MGSMPLEQRS QHCKPEEGLE ARGEALGLVG AQAPATEEQE AASSSSTLVE VTLGEVPAAE SPDPPQSPQG ASSLPTTMNY PLWSQSYEDS SNQEEEGPST FPDLESEFQA ALSRKVAELV HFLLLKYRAR EPVTKAEMLG SVVGNWQYFF PVIFSKASSS LQLVFGIELM EVDPIGHLYI FATCLGLSYD GLLGDNQIMP KAGLLIIVLA IIAREGDCAP EEKIWEELSV LEVFEGREDS ILGDPKKLLT QHFVQENYLE YRQVPGSDPA CYEFLWGPRA LVETSYVKVL HHMVKISGGP HISYPPLHEW VLREGEE
Target/Specificity MAGEA3
Application Notes In 20 mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 10% glycerol, 100mM NaCl
Format Liquid
Storage -20°C;Liquid
Citations (0)

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Background

Melanoma-associated antigen 3, also known MAGEA3, is a member of the MAGE gene family, which comprises 12 known genes, of which 6 are expressed in tumors. The MAGE genes were initially isolated from different kinds of tumors, and based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. MAGEA3 is a tumor-specific antigen widely expressed in solid and hematologic malignancies, but not in normal tissues, with the exception of testis and placenta. Therefore, MAGEA3 is an excellent candidate tumor antigen. Recombinant human MAGEA3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

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$ 180.00
$ 335.00
Cat# PBV11488r-10
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